Relic Synergy Guide

Quick facts:

Relic Synergy Guide

Relic Synergy Guide

Type

Strategy Guide

Related Systems

Relics, Perks, Mastery

Enhances

Build Strength, Combat Effectiveness

Found In

Chests, Chambers, Torture Chambers

Best For

Mid-to-Late Game Optimization

The Relic Synergy Guide helps players understand how to combine Relics effectively in 33 Immortals to maximize combat performance and build specialization. Relics provide passive bonuses or conditional effects that, when paired intelligently, can transform your Loadout from average to exceptional.

Overview

Relics are core progression items that modify or enhance your gameplay. Each relic grants a unique effect — such as increased damage, healing, status application, or energy regeneration. While relics are powerful on their own, true strength lies in combining them to support your weapon type, Stats, and Special Abilities.

Core Concepts of Synergy

• Combine relics that scale with the same stat (e.g., multiple relics that boost or benefit from Attack)
• Match relic effects with your weapon’s mechanics (e.g., passive healing for tanks, critical hit boosts for daggers)
• Avoid relic overlap that offers diminishing returns unless stacking is intentional
• Choose relics that support your role in the team (DPS, tank, or support)

Synergy by Role

DPS (Damage Dealers)

• Prioritize relics that increase critical hit chance, damage output, or attack speed
• Stack effects like On-Hit Burn, Marked Damage Bonus, or Low-Health Burst
• Combine with Daggers of Greed or Bow of Hope for rapid hits and high output

Recommended Relic Combos:

• Greed Generator + Critical Surge + Combo Multiplier
• Shattering Arrows + Auto Recall + Marked Finisher

Tank / Frontliner

• Focus on relics that grant shielding, damage reduction, health regeneration, or crowd control effects
• Stack vitality-scaling relics with abilities like Guard or taunt mechanics
• Works best with Sword of Justice and Vitality-boosting Mastery traits

Recommended Relic Combos:

• Reinforced Body + Reactive Armor + Stagger Pulse
• Divine Shield + Heavy Slam Buff + Final Justice

Support / Control

• Choose relics that enhance Empathy, prolong status effects like Slowed, or improve Co-op Powers
• Combine area debuff relics with energy regeneration or healing effects
• Perfect for Staff of Sloth users and utility builds

Recommended Relic Combos:

• Torpor Extension + Slow Aura + Super Slow Amplifier
• Team Heal Burst + Empathy Echo + Sloth Charge Booster

Weapon-Specific Synergies

Each weapon benefits from specific relic combinations based on its mechanics:

• Sword of Justice – Seek relics that refund or boost Justice, or amplify Stagger
• Daggers of Greed – Use crit-based relics and effects that trigger on consecutive hits
• Bow of Hope – Combine projectile modifiers with effects that trigger on arrow recall
• Staff of Sloth – Focus on slow amplification, passive regeneration, and AoE synergy

Situational Relics

• Some relics are stronger in solo vs. co-op play
• Certain relics work best in Chambers or Torture Chambers due to enemy density
• Adjust your relic picks depending on zone threats (e.g., AoE for Inferno, sustain for Paradiso)

Tips for Optimizing Synergy

• Build around your core weapon identity — not all relics suit every playstyle
• Use Fragments to reroll relics that don’t align with your intended build
• Synergize with Perks that complement relic effects (e.g., enhanced dodge triggering poison)
• Prioritize relics that scale with your highest Stat (Attack, Vitality, Empathy)

Summary

The Relic Synergy Guide unlocks the true potential of your rebellion. By crafting your relic set with intention and awareness, you ensure every swing, shot, or cast pushes you further into legendary territory. In *33 Immortals*, the divine are strong — but synergy makes mortals stronger.