Boss Relics

Quick facts:

Boss Relics

Boss Relics

Type

Relics

Usage

Passive boss-focused enhancements

Obtained From

Torture Chambers, Elite Enemies, Relic Recycling

Duration

Lasts for the full run

Stackable

Yes

Boss Relics are a specialized type of Relics in 33 Immortals that provide powerful passive effects specifically designed to give players an edge in boss battles. These relics enhance damage, healing, co-op power, and utility when fighting bosses, and are considered some of the most impactful relics in the game’s late-stage content.

Overview

Boss Relics activate automatically upon being picked up and remain active throughout the current run. They do not need to be equipped or activated manually. These relics are especially useful in areas like Inferno, Purgatorio, and Paradiso, where powerful boss encounters are central to progression.

How to Acquire

Players can obtain Boss Relics through:

• Clearing Torture Chambers
• Defeating elite enemies
• Recycling unwanted relics to reroll drops

Each relic drop is randomized, so it is important to adapt to what becomes available during each rebellion run.

List of Known Boss Relics

Defiled Crucifixion Nails

• Doubles all damage dealt to bosses when their current health bar drops below 30%.

All Seeing Saucer

• Increases damage dealt to bosses by 10% per level of Co-Strike, up to a maximum of 120%.

Anointed Chalice

• Reduces damage taken from bosses for each nearby player.

Coffer of the Devoted

• Increases damage dealt by all players by 50% when a boss is stunned, weakened, exposed, or marked.

Empyreal Light

• All players apply 100% of their status effects on bosses, ensuring debuffs are always applied.

Polished Monstrance

• When a boss loses a full health bar, all players gain back 25% of their co-op power.

Shrunken Papal Heart

• Fully heals all players upon entering a boss lair.

Wax Death Mask

• Heals all players for 10% of their maximum health each time a boss loses a full health bar.

Strategy

Boss Relics can turn the tide of high-stakes encounters by:

• Granting powerful damage boosts at critical phases
• Enhancing survival and healing during boss mechanics
• Empowering co-op synergy through passive regeneration or status effects

Choosing the right relics based on team composition and boss mechanics is key to raid success. Combining damage-boosting relics like the Defiled Crucifixion Nails with healing relics like the Wax Death Mask allows teams to maintain both pressure and sustain throughout multi-phase boss battles.

Summary

Boss Relics are among the most valuable pickups in 33 Immortals. They offer significant advantages during key encounters and should be prioritized when preparing for high-tier raids. Whether maximizing damage or reinforcing team defense, Boss Relics are critical to surviving divine judgment.